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Here is a simplified factory method for creating a readonly memory mapped file to a path: public static MemoryMappedFile MemFile(string path) { return MemoryMappedFile.CreateFromFile( //include a readonly shared stream File.Open(path, FileMode.Open, FileAccess.Read, FileShare.Read), //not mapping to a name null, //use the file's actual size 0L, //read only access MemoryMappedFileAccess.Read, //not configuring security null, //adjust as needed HandleInheritability.None, //close the previously passed in stream when done false); } To create and use the full stream: using (var memFile = MemFile(path)) using (var stream = memFile.CreateViewStream(0L, 0L, MemoryMappedFileAccess.Read)) { //do stuff with your stream }.